Cortisol Cushings Test

Concerned about Cushing’s syndrome? Detect high cortisol and underlying adrenal conditions early with our 3-month Cortisol Over Time (COT) test.

Fast, accurate, and non-invasive, our test provides the most comprehensive measure of your cortisol levels, aiding in the early detection of Cushing’s syndrome and chronic stress.

If you have been diagnosed with Cushing’s syndrome then this test can help you to manage your cortisol levels and future risk of illness. Take control of your health today.

No blood and no needles

No blood. No needles.

Quick and easy

Quick and easy collection with fast results

Free UK postage

FREE UK postage

No repeated samples

No need for repeated samples

Clinically proven

Clinically proven with expert support

Cortisol Cushings Test £149.00 £99.00

About This Test

Sample method: Hair

Cortigenix’s Cortisol Over Time (COT) test is a screening test that measures your cortisol levels over the past 3-months.

This test can be used to rule out underlying adrenal problems such as Cushing’s syndrome and provides a clear picture of how your cortisol levels may be impacting your health and future risk of illness.

What to know

A hair sample is used for this test because unlike blood, saliva and urine tests which measure short-term cortisol levels, this test measures your cortisol levels over the past 3-months.

You will need to provide a hair sample that is a minimum 1cm in length.

We will send you your home collection kit with easy-to-follow instructions so that you can take your sample from home.

Signs and symptoms of high cortisol and Cushing’s Syndrome

Cushings syndrome is a condition caused by having too much cortisol in your body. Symptoms of Cushing’s can be difficult to detect because early symptoms are similar to those of many other conditions. You may not show all symptoms.

  • Weight gain
  • Increase fat on your chest or tummy but slim arms and legs
  • A build-up of fat on your back or neck (i.e., ‘buffalo hump’
  • A red, puffy, rounded face
  • Skin that bruises easily
  • Large purple stretch marks
  • Weakness in your upper arms and thighs
  • High blood pressure
  • Chronic fatigue
  • Feeling tired and drowsy
  • Acne
  • Loss of appetite and unintentional weight loss
  • Dizziness when standing
  • Sleeplessness
  • Craving salty foods
  • Feeling sick
  • Low mood
  • A frequent need to pee
  • Increased thirst
  • Headaches
  • Brain Fog
  • Abdominal pain
  • A higher temperature
  • Irregular periods

Who should take the test

You should take this test if you want to check your cortisol levels or detect an underlying adrenal condition. Take this test if:

  • You have any of the signs and symptoms of Cushing’s syndrome
  • You have Cushing’s and would like to monitor your cortisol levels over time
  • You want to manage how your lifestyle may be impacting on your cortisol levels
  • You are feeling stressed

How is this test different to other cortisol tests?

Cortigenix’s Cortisol Over Time (COT) test measures your long-term average cortisol levels over the past 3 months. This test is different to ‘acute’ blood, saliva and urine tests, which only measure your short-term cortisol levels over minutes to hours.

Here are some important things you should know:

Chronic long-term measurement: Hair cortisol levels reflect cortisol production over the past 3-months providing a comprehensive overview of adrenal function. This is particularly useful for people that have signs and symptoms of Cushing’s syndrome or would like to manage their condition better.

Helps prevent misdiagnosis and missed diagnosis of Addison’s disease: Cortisol levels can change from minute-by-minute and from day-to-day which means that your results can vary on different days, which can lead to misdiagnosis and missed diagnosis of Cushing’s syndrome. Cortigenix’s Cortisol Over Time (COT) test measures your average cortisol levels over the past 3-months. This is a more accurate way of checking your cortisol levels.

Non-invasive testing: Unlike blood tests, which may require multiple samples and can be uncomfortable Cortigenix’s cortisol test is non-invasive and only requires a small hair sample.

Cortisol monitoring: By tracking changes in hair cortisol levels over time you can help to identify lifestyle factors that may be impacting on your cortisol levels and reduce your risk of an adrenal crisis or other health problems.

More accurate than blood, saliva and urine cortisol tests: Hair is most accurate way to measure cortisol function over time. Cortisol levels in blood, saliva and urine can be influenced by a variety of factors, including acute stress, physical activity, and medications, whereas cortisol levels in hair reflect a more stable measure of long-term cortisol exposure.


5 Stars

After years of struggling to manage my symptoms and find the root cause of my unexplained weight gain and fatigue, I was recommended Cortigenix’s cortisol test by my doctor. This test provided the clarity I desperately needed in my journey with Cushing's syndrome. No more invasive procedures or inconclusive results. It pinpointed the elevated cortisol levels, and was a vital part of my diagnosis and treatment plan. A game-changer for those with suspected adrenal conditions.

H Murray

4 Stars

Cortigenix’s cortisol test has revolutionized how I approach my battle with Cushing's. Gone are the days of endless doctor visits and unanswered questions. This test offered a non-invasive solution to monitor cortisol levels accurately, empowering me to take control of my health. It's a lifeline for anyone trying to get answers and navigate the complexities of Cushing's syndrome. Highly recommend it.

F Ayling


How it works

We make finding out simple. No blood. No needles. All from home. We just need a small sample of your hair!

Buy your test

Step 1

Buy your test

Prepare your hair sample

Step 2

Prepare your hair sample

Send your sample to us

Step 3

Send your sample to us

Get your results

Step 4

Get your results


Frequently asked questions

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How does the COT test track my inner health over time?

We use your 'lifestyle hormone' cortisol to see what's been happening inside your body over several months. Your cortisol levels accumulate in your hair as it grows - each 1cm of hair growth provides one month's worth of cortisol. This enables you to understand what's been going on inside your body over several months, and not just a snapshot.

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What makes Cortigenix's technology unique?

Our unique COT test is the only test in the world developed by independent scientists to assess your cortisol levels over several months. By tracking your cortisol levels over 84 days our test provides up to 42x more insight in to your inner health compared to traditional blood and saliva tests - which can only assess cortisol levels over minutes to hours. Which means that traditional blood and saliva tests do not provide an accurate picture of how your cortisol levels are impacting your long term health.

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How do I provide a sample?

Your hair sample is taken from the back of your head. You need a minimum of 1cm of hair in length (roughly half a pencil width in thickness) to provide a sample. Your COT test includes a test tube, a hair tie and a return envelope for you to return your sample to us.

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How are my results delivered?

Your results will be delivered through your personalised portal within 7-10 working days. We will notify you via email when your results are ready.

Take control of stress. One simple test.


Call us on 01526 861272

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